20180305_publikation_amf_migration_vdhi.pdf - The Asylum and Migration Fund: A tool for more humane, transparent and effective asylum and migration policies in the EU? February 2019 The undersigned organisations call on the co-legislators to consider a number of key asks to make sure that the Asylum and Migration Fund (AMF) plays a considerable role in meeting its stated objectives, including

 
5 Term Description ML Machine Learning MME Mobile Mobility Entity mMTC Mobile Machine Type Communications MO SMS Mobile-Originated Short Message . Hula hop sportowe

Mar 5, 2018 · The momentum to improve international migration statistics has never been stronger. For many years, the General Assembly has called for accurate, timely and disaggregated statistics on international migration. The adoption of the 2030 Agenda for Sustainable Development and the New York Declaration for Refugees and Migrants have added further urgency to the need to strengthen national ... • Venues to discuss migration data and disaggregation by migratory status • Capacity development 4.0 ( PARIS21) • Use of big data and geospatial information ( UN‐GGIM, UN GWG on Big Data for Official Statistics) • Mapping of global indicators by member states in their context. DOC-2012-02 Corporate governance and executive compensation in companies referring to the AFEP-MEDEF code - Consolidated presentation of the recommendations contained in the AMF annual reports; DOC-2015-05 Major Asset Disposals and Acquisitions; DOC-2011-17 AMF 2011 annual report on corporate governance and executive compensation• Venues to discuss migration data and disaggregation by migratory status • Capacity development 4.0 ( PARIS21) • Use of big data and geospatial information ( UN‐GGIM, UN GWG on Big Data for Official Statistics) • Mapping of global indicators by member states in their context. Bat migrations have been studied for a long time, but large areas remain poorly explored in this regard. This note reports a record migration distance of the Nathusius’ pipistrelle – 2486 km from Russia to the French Alps. This distance exceeds the previous record flight from Latvia to Spain by 260 km. Hibernating colonies of Nathusius’ pipistrelle are known in the Caucasus. However, our ... Analysis of the signaling pathway triggered by AMF demonstrated phosphorylation of ERK 1/2 and JNK 1/2/3, leading to activation of c-Fos and c-Jun [16]. In this report, we describe for the first time the role of AMF in promoting MSC migration. Our results demonstrate that AMF produced by HCC is involved in migration of MSCs. Moreover, Migration Utility product. The source code remains in the original library 4) IBM Migration Utility for z/OS creates IBM standard COBOL syntax from EasyTrieve Plus language statements, without having to have the EasyTrieve product installed. The IBM Migration Utility runs in place of the EasyTrieve Plus interpreter. Source code, written inJul 24, 2018 · To obtain further evidence for GPI/AMF acting as autocrine stimulator of glioblastoma cell migration as well as to evaluate its role in vivo, we silenced GPI/AMF expression. Initially, GS-11, GS-12, and G55 cells were transduced with 6 different shRNAs targeting GPI/AMF (shAMF) or with nonsilencing control shRNA (shControl). AMF produced by HCC induce migration of MSCs from different sources AMF enhances BM-MSC migration by stimulating A 55 KDa soluble AMF form was detected in the conditioned endothelial cell adhesion and modulating relevant genes medium of cell culture monolayers (CCM) and SC tumors (TCM) Potent and specific MSC migration toward HCC is critical ...The Asylum Migration and Integration Fund (AMF) focuses on managing people flows throughout the EU. Migration into and out of the EU has increased dramatically in the last few decades. Furthermore, the number of asylum seekers attempting to find refuge in Europe has greatly risen.Container 1 had no AMF inoculation (Ctrl/Ctrl and Ctrl/pathogen treatments in Table 1), and containers 2, 3 and 4 had 101-14, 5C and Schwarzmann AMF communities (AMF/Ctrl and AMF/pathogen treatments), respectively. The pumice in each container was inoculated with approximately 10,000 spores (5 spores/g) at the corresponding AMF community ...Importance of Migration Statistics The importance of migration data to decision makers, planners, international organizations and other users is to identify its size, levels and trends in Jordan. The aim is to contribute to making the right decisions and necessary measures to tackle and organize this phenomenon. The country can also directDefine and frame the use of AMF in non EU countries The AMF proposal enables third countries associated to the fund to be direct beneficiaries of Member States’ national programmes for the purpose of managing migration, and includes measures regarding readmission procedures, return and reintegration, as well as resettlement schemes.Jan 7, 2021 · At a Glance 01-07-2021. As part of the 2021-2027 Multiannual Financial Framework (MFF), the Commission adopted a proposal for a new regulation establishing the Asylum and Migration Fund (AMF). The aim of the proposal is to contribute to the efficient management of migration flows in the European Union. The European Parliament is due to vote at ... 2 Each of these questions may have appeared futuristic not so long ago. But today, there is a rapidly growing consensus that artificial intelligence can revolutionise human The Asylum and Migration Fund: A tool for more humane, transparent and effective asylum and migration policies in the EU? February 2019 The undersigned organisations call on the co-legislators to consider a number of key asks to make sure that the Asylum and Migration Fund (AMF) plays a considerable role in meeting its stated objectives, includingNov 8, 2008 · A transwell migration assay was performed in various AMF/PGI stable cell lines. Wild-type AMF/PGI induces a significant increase in cell migration. Expression of AMF/PGI mutants V101M and R472H reduced migration efficiency, as well as mutant R347H. Mutant R273H was unable to stimulate migration (Fig. 7 A). Therefore, AMF/PGI enzymatic activity ... Define and frame the use of AMF in non EU countries The AMF proposal enables third countries associated to the fund to be direct beneficiaries of Member States’ national programmes for the purpose of managing migration, and includes measures regarding readmission procedures, return and reintegration, as well as resettlement schemes. International Migration and Development (HLD) in September 2006. Taken together, these initiatives signal both a growing consensus that interna-tional migration can have important impacts on development, and that it is an important opportunity to develop policy interventions that will help realize the full potential of international migration.AMF - Objectives Effective management of migration flows Common European Asylum System legal migration Integration and Return Solidarity and responsibility sharing Ensure efficient and uniform application of the Union acquis on asylum Set up and develop integration strategies at local/regional level (two way dynamic process, specific needs,Apr 15, 2014 · Methods. Production of AMF by HCC tumors was evaluated by western analysis. The effects of AMF on MSCs from different sources (bone marrow, adipose tissue and perivascular cells from umbilical cord) were analyzed using in vitro migration assay; metalloproteinase 2 (MMP2) activity and expression of critical genes were studied by zymography and qRT-PCR, respectively. Define and frame the use of AMF in non EU countries The AMF proposal enables third countries associated to the fund to be direct beneficiaries of Member States’ national programmes for the purpose of managing migration, and includes measures regarding readmission procedures, return and reintegration, as well as resettlement schemes. The Asylum, Migration and Integration Fund (AMIF) is set up for the period 2021-2027, with a total of EUR 9.88 billion.The Fund aims to further boost national capacities and improve procedures for migration management, as well as to enhance solidarity and responsibility sharing between Member States, in particular through emergency assistance and the relocation mechanism.• Venues to discuss migration data and disaggregation by migratory status • Capacity development 4.0 ( PARIS21) • Use of big data and geospatial information ( UN‐GGIM, UN GWG on Big Data for Official Statistics) • Mapping of global indicators by member states in their context. On the other hand, migration is the process of leaving one's own country or moving within a state to live elsewhere, regardless of the migrant's legal status, the nature of their journey ...Jul 24, 2018 · To obtain further evidence for GPI/AMF acting as autocrine stimulator of glioblastoma cell migration as well as to evaluate its role in vivo, we silenced GPI/AMF expression. Initially, GS-11, GS-12, and G55 cells were transduced with 6 different shRNAs targeting GPI/AMF (shAMF) or with nonsilencing control shRNA (shControl). States on asylum and migration, in particular by supporting funds to pool best practice on asylum. This can be done in part by setting up networks and exchanging information on legal migration and the integration of third-country nationals. 1.10 The EESC welcomes the importance given to flexibility in both funds, as this entails acknowledging This paper demonstrates the application of the AMF model to simulate delamination migration in composite laminates by refining the fidelity of FE model locally in order to predict damage progression. The numerical results obtained from the AMF model are validated with experiments and full 3D models.1 INTRODUCTION. The COVID-19 pandemic has profoundly altered people's daily lives. Various measures implemented by governments to limit the spread of the virus ranged from social distancing (e.g., closure of restaurants, recreational facilities, childcare and educational facilities) to restrictions of international and national travel and lockdowns (Alipour et al., 2020; Karako et al., 2020 ...Prominence is given to theoretical perspectives of international migration and the classification of migration theories. In addition, shortcomings of migration theories are examined. International ...The ability to predict accurately the levels of unsteady forcing on turbine blades is critical to avoid high-cycle fatigue failures. Further, a demonstrated ability to make accurate predictions ...Mar 5, 2018 · IBM Migration Utility V04.01.00 Program Number 5655-MGU FMID HMGU410 for Use with z/OS OS/390 Document Date: September 2012 GI13-2909-00. Note Feb 1, 2023 · This paper demonstrates the application of the AMF model to simulate delamination migration in composite laminates by refining the fidelity of FE model locally in order to predict damage progression. The numerical results obtained from the AMF model are validated with experiments and full 3D models. The Asylum, Migration and Integration Fund (AMIF) is set up for the period 2021-2027, with a total of EUR 9.88 billion.The Fund aims to further boost national capacities and improve procedures for migration management, as well as to enhance solidarity and responsibility sharing between Member States, in particular through emergency assistance and the relocation mechanism.migration in a systematic manner (professionally or otherwise), including how we can optimally handle this issue in the future. The ACVZ also hopes that this report will bring more depth to the societal debate regarding current and future migration policy. The migration debate is currently heavily influenced by theArbuscular mycorrhizal fungi (AMFs) play a vital role in ecosystems, especially in ecosystem variability, diversity, and function. Understanding the AMF diversity, distribution, and their driver at different altitudinal gradients is a benefit for understanding the ecological function of AMF in mountain ecosystems. In this study, we explored the AMF molecular diversity and their distribution ...Lastly, in order to send applicable and appropriate event information, the AMF connects to Lawful Intercept (LI) systems. While the information could be stored in another manner, the AMF typically queries the 5G Service-Based Architecture’s (SBA’s) Network Repository Function (NRF) to discover and select available SMF instances.Zusammenfassung. Ziel der Untersuchung ist es zum einen abzuschätzen, inwieweit das inländische Potenzial zur Rekrutierung von Arbeitskräften für die Altenpflege in Deutschland zur Deckung des prognostizierten Bedarfs im Jahr 2030 ausreicht. Zum anderen werden die Chancen und Hemmnisse der Rekrutierung ausländischer Pflegekräfte sowohl ...2. LEGAL BASIS, SUBSIDIARITY AND PROPORTIONALITY • Legal basis Article 3(2) of the Treaty on European Union provides that ‘the Union shall offer its citizens an area of freedom, security and justice without internal frontiers, in which the free movement of persons is ensured in conjunction with appropriate measures with respect to external border controls, asylum, immigration and the ...To ensure consistency, AMF and other internal affairs funds should not be used to establish new detention infrastructures or to detain children or their families. The future of the Asylum, Migration and Integration Fund Our call for more humane, transparent and effective resources for asylum and migration in the Union November 2019 States on asylum and migration, in particular by supporting funds to pool best practice on asylum. This can be done in part by setting up networks and exchanging information on legal migration and the integration of third-country nationals. 1.10 The EESC welcomes the importance given to flexibility in both funds, as this entails acknowledging Migration and Integration Fund (AMIF), the undersigned organizations wish to reiterate and update their priorities in light of the new Pact on Migration and Asylum. The present statement builds upon previous collective recommendations and concerns relating to the AMIF proposal highlighted in February 2019 and November 2019. Research revealed a major migration to the island of Great Britain 3,000 years ago, which offers fresh insights into the languages spoken at the time, the ancestry of present-day England and Wales, and even ancient habits of dairy consumption. Learn more about the British migration.Jun 17, 2021 · Smooth interworking between EPS roaming and 5GS roaming will therefore be essential. Roaming extends the coverage of a home operator’s services, allowing its mobile users to use those services within another operator’s network, which may be in another country (international roaming) or in the same country (national roaming). Sep 2, 2020 · First, from a mobilities perspective, migration is seen as just one of many forms of movement that shape and produce the daily lives we live. From a migration framework, however, mobility is mostly regarded as the migratory process – a phase of movement – from a particular place of origin towards a destination. international community to: assist in the meeting of operational challenges of migration; advance understanding of migration issues; encourage social and economic development through migration; and uphold the human dignity and well-being of migrants. Publisher: International Organization for Migration 17 route des Morillons P.O. Box 17 1211 ... Jul 24, 2013 · Zusammenfassung. Ziel der Untersuchung ist es zum einen abzuschätzen, inwieweit das inländische Potenzial zur Rekrutierung von Arbeitskräften für die Altenpflege in Deutschland zur Deckung des prognostizierten Bedarfs im Jahr 2030 ausreicht. Zum anderen werden die Chancen und Hemmnisse der Rekrutierung ausländischer Pflegekräfte sowohl ... Sollte die VDHI einen Interessenkonflikt nicht vermeiden können, werden die Kunden auf die Art des Konfliktes und seine Ursachen hingewiesen. Unvermeidbare Interessenkonflikte können sich daraus ergeben, dass Produkte der VDHI in die Investmentfonds erworben werden, für deren Verwaltung die VDHI eine Verwaltungsvergütung erhält.6. Diet. There’s a laundry list of foods known to trigger a migraine attack, the most common ones being foods that contain histamine and MSG, chocolate, cheese and other dairy products, artificial sweeteners (e.g. aspartame), caffeine, cured meats, and anything with a strong smell.diminished considerably. Institutional barriers to migration (for example, land tenure security and access to credit) are also changing, albeit more slowly. Taken together, these trends provide good reason to regularly revisit migration trends and associated labor market developments as new data become available.We demonstrated that AMF/PGI transactivates the MMP-3 gene promoter through AP-1. The transactivation and induction of cell migration effect of AMF/PGI directly correlates with its enzymatic activity. Various analyses showed that AMF/PGI stimulated the Src-RhoA-PI3-kinase signaling pathway, and these three signaling molecules could form a complex.Analysis of the signaling pathway triggered by AMF demonstrated phosphorylation of ERK 1/2 and JNK 1/2/3, leading to activation of c-Fos and c-Jun [16]. In this report, we describe for the first time the role of AMF in promoting MSC migration. Our results demonstrate that AMF produced by HCC is involved in migration of MSCs. Moreover,Analysis of the signaling pathway triggered by AMF demonstrated phosphorylation of ERK 1/2 and JNK 1/2/3, leading to activation of c-Fos and c-Jun [16]. In this report, we describe for the first time the role of AMF in promoting MSC migration. Our results demonstrate that AMF produced by HCC is involved in migration of MSCs. Moreover, Nov 12, 2018 · 1.Increased glycolysis is linked with increased cell migration and invasion in glioblastoma cells. 2.The glycolysis enzyme GPI/AMF may serve as a target for antimetabolic and anti-invasive therapy. 3.Despite reducing tumor invasion, GPI/AMF targeting may have unwanted growth stimulatory effects. Define and frame the use of AMF in non EU countries The AMF proposal enables third countries associated to the fund to be direct beneficiaries of Member States’ national programmes for the purpose of managing migration, and includes measures regarding readmission procedures, return and reintegration, as well as resettlement schemes. county and inter-state migration of pre-war birth cohorts in the U.S. Their analysis shows that married individuals have lower rates of migration than do singles, and that the rates of migration decrease significantly as family size increases. The authors conclude that two factors are responsible for this reduction.Apr 15, 2014 · AMF produced by HCC exerts a potent role as chemotactic protein. Cell migration of BM-MSCs (A), HUCPVCs (B) or AT-MSCs (C) towards TCM derived from HuH7 (gray bars) or HC-PT-5 (black bars ... Sustainable Development Goals (SDGs) include migration-related targets on labour standards, human trafficking, transfer costs of remittances, etc. Target 10.7 calls on countries to facilitate safe, orderly and regular migration and to implement well-managed migration policies. Keeping track of the implementationMar 5, 2018 · IBM Migration Utility V04.01.00 Program Number 5655-MGU FMID HMGU410 for Use with z/OS OS/390 Document Date: September 2012 GI13-2909-00. Note The Asylum Migration and Integration Fund (AMF) focuses on managing people flows throughout the EU. Migration into and out of the EU has increased dramatically in the last few decades. Furthermore, the number of asylum seekers attempting to find refuge in Europe has greatly risen.Mar 29, 2022 · 1 INTRODUCTION. The COVID-19 pandemic has profoundly altered people's daily lives. Various measures implemented by governments to limit the spread of the virus ranged from social distancing (e.g., closure of restaurants, recreational facilities, childcare and educational facilities) to restrictions of international and national travel and lockdowns (Alipour et al., 2020; Karako et al., 2020 ... Research revealed a major migration to the island of Great Britain 3,000 years ago, which offers fresh insights into the languages spoken at the time, the ancestry of present-day England and Wales, and even ancient habits of dairy consumption. Learn more about the British migration.AMF Plus device and it will automatically receive the right firmware, licenses, and configuration from the Master. This enables plug-and-play replacement for end-of-life products. AMF Plus is a sophisticated suite of management tools that provide a simplified approach to network management. international community to: assist in the meeting of operational challenges of migration; advance understanding of migration issues; encourage social and economic development through migration; and uphold the human dignity and well-being of migrants. Publisher: International Organization for Migration 17 route des Morillons P.O. Box 17 1211 ...Mar 5, 2018 · migration is from Ghoramara, so much so that even some available land lies fallow and neglected, which makes it more vulnerable to saline water inundation because no one repairs the embankments ... Mar 5, 2018 · migration is from Ghoramara, so much so that even some available land lies fallow and neglected, which makes it more vulnerable to saline water inundation because no one repairs the embankments ... This paper surveys our understanding of how migration affects growth and inequality through the impact on migrants themselves as well as on the destination and origin countries. JEL Classification Numbers: F22, O15, F63, J61. Keywords: International Migration, Inequality, Economic growth. Authors’ E-Mail Addresses:Nazi Forced Labor and Migration«, the data of more than 1,700 people have now been evaluated and made accessible for the very first time. The project provides three different ways to explore the life paths of the people concerned: an Interactive Map, group biographies illustrated with the aid of Story Maps, and workshop materialsTo ensure consistency, AMF and other internal affairs funds should not be used to establish new detention infrastructures or to detain children or their families. The future of the Asylum, Migration and Integration Fund Our call for more humane, transparent and effective resources for asylum and migration in the Union November 2019 Mar 5, 2018 · Migration Utility product. The source code remains in the original library 4) IBM Migration Utility for z/OS creates IBM standard COBOL syntax from EasyTrieve Plus language statements, without having to have the EasyTrieve product installed. The IBM Migration Utility runs in place of the EasyTrieve Plus interpreter. Source code, written in First, from a mobilities perspective, migration is seen as just one of many forms of movement that shape and produce the daily lives we live. From a migration framework, however, mobility is mostly regarded as the migratory process – a phase of movement – from a particular place of origin towards a destination.The influences of species, CO2 concentrations and planting year on AMF colonization were associated with their effects on both soil nutrient and AMF community, and the former may be more important ...Analysis of the signaling pathway triggered by AMF demonstrated phosphorylation of ERK 1/2 and JNK 1/2/3, leading to activation of c-Fos and c-Jun [16]. In this report, we describe for the first time the role of AMF in promoting MSC migration. Our results demonstrate that AMF produced by HCC is involved in migration of MSCs. Moreover, 5 Term Description ML Machine Learning MME Mobile Mobility Entity mMTC Mobile Machine Type Communications MO SMS Mobile-Originated Short Message Sollte die VDHI einen Interessenkonflikt nicht vermeiden können, werden die Kunden auf die Art des Konfliktes und seine Ursachen hingewiesen. Unvermeidbare Interessenkonflikte können sich daraus ergeben, dass Produkte der VDHI in die Investmentfonds erworben werden, für deren Verwaltung die VDHI eine Verwaltungsvergütung erhält.Mar 5, 2018 · The momentum to improve international migration statistics has never been stronger. For many years, the General Assembly has called for accurate, timely and disaggregated statistics on international migration. The adoption of the 2030 Agenda for Sustainable Development and the New York Declaration for Refugees and Migrants have added further urgency to the need to strengthen national ... States on asylum and migration, in particular by supporting funds to pool best practice on asylum. This can be done in part by setting up networks and exchanging information on legal migration and the integration of third-country nationals. 1.10 The EESC welcomes the importance given to flexibility in both funds, as this entails acknowledgingNov 12, 2018 · 1.Increased glycolysis is linked with increased cell migration and invasion in glioblastoma cells. 2.The glycolysis enzyme GPI/AMF may serve as a target for antimetabolic and anti-invasive therapy. 3.Despite reducing tumor invasion, GPI/AMF targeting may have unwanted growth stimulatory effects. Research revealed a major migration to the island of Great Britain 3,000 years ago, which offers fresh insights into the languages spoken at the time, the ancestry of present-day England and Wales, and even ancient habits of dairy consumption. Learn more about the British migration.

Autocrine motility factor (AMF) is a tumor-secreted cytokine that acts as a motogen as well as a mitogen via a receptor-mediated signaling pathway(s). Expression of the AMF receptor (AMF-R) in normal cells is regulated by cell contact whereas in transformed cells AMF-R is constitutively expressed irrespective of cell density.. Ifivjqt

20180305_publikation_amf_migration_vdhi.pdf

States on asylum and migration, in particular by supporting funds to pool best practice on asylum. This can be done in part by setting up networks and exchanging information on legal migration and the integration of third-country nationals. 1.10 The EESC welcomes the importance given to flexibility in both funds, as this entails acknowledgingTo obtain further evidence for GPI/AMF acting as autocrine stimulator of glioblastoma cell migration as well as to evaluate its role in vivo, we silenced GPI/AMF expression. Initially, GS-11, GS-12, and G55 cells were transduced with 6 different shRNAs targeting GPI/AMF (shAMF) or with nonsilencing control shRNA (shControl).The momentum to improve international migration statistics has never been stronger. For many years, the General Assembly has called for accurate, timely and disaggregated statistics on international migration. The adoption of the 2030 Agenda for Sustainable Development and the New York Declaration for Refugees and Migrants have added further urgency to the need to strengthen national ...Thus, the authors call for new modes of caring for (big) data when researching migrants’ digital practices in the configuration of migration and borders. Besides taking proper care of research participants’ privacy, autonomy, and security, this also spans carefully establishing analytically sustainable environments for the respective data sets.The Asylum Migration and Integration Fund (AMF) focuses on managing people flows throughout the EU. Migration into and out of the EU has increased dramatically in the last few decades. Furthermore, the number of asylum seekers attempting to find refuge in Europe has greatly risen.Catalog; For You; The Guardian Australia. Housing report says migration may need to be cut to preserve quality of life 2018-03-05 - Gareth Hutchens . One of Australia’s most respected thinktanks has weighed into the population growth debate, saying the federal government needs to develop an explicit population policy that defines the “appropriat­e” level of migration, and it may need to ...2. LEGAL BASIS, SUBSIDIARITY AND PROPORTIONALITY • Legal basis Article 3(2) of the Treaty on European Union provides that ‘the Union shall offer its citizens an area of freedom, security and justice without internal frontiers, in which the free movement of persons is ensured in conjunction with appropriate measures with respect to external border controls, asylum, immigration and the ... 7. Click Finish. 8. Save your work and click Restart Now to complete the installation if prompted. 9. Click New Server. 10. Enter vditest.jmhconnect.net then click Connect.IBM Program Directory for IBM Migration Utility V03.02.00 Program Number 5697-N44 FMID HMGU320 for Use with z/OS OS/390 Document Date: July 2009 GI10-3374-01Amazon Web Services 5G Network Evolution with AWS 2 communication service provider (CSP) in the telecom industry. Openness has been a long-standing requirement of CSPs and AWS Cloud provides exactly that – strong three-day weekend to allow for the migration and unforeseen challenges, the system and data migration was complete in just 14 hours. The go-live decision was made on day two. The system went live on schedule with a normal production workload. The phase two migration, planned for a normal two-day weekend, was successfully completed in under 24 ... Move the image to the Proxmox VE Server. Plug a USB Hard Drive into the server. From the Proxmox VE command line: mkdir /mnt/usb. mount /dev/sdc1 /mnt/usb/. ls /mnt/usb. You should see the contents of the USB drive. In my case, the vmdk file was located in /mnt/usb/windows-server/.These reciprocal effects are cantly overexpressed in the classical and mesenchymal glio- similar to those observed previously for the same cell lines blastoma subtypes, which carry a worse prognosis,12 and in response to hypoxia.3,4 1598 Kathagen-Buhmann et al. GPI/AMF function in glioblastoma A B GPI/AMF AMFR 100 100 High expression High ... .

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